Thomas L Vaughan, MD, MPH - Research & Publications

<<option chkGenerateAnRssFeed>> GenerateAnRssFeed\n<<option chkOpenInNewWindow>> OpenLinksInNewWindow\n<<option chkSaveEmptyTemplate>> SaveEmptyTemplate\n<<option chkToggleLinks>> Clicking on links to tiddlers that are already open causes them to close\n^^(override with Control or other modifier key)^^\n<<option chkHttpReadOnly>> HideEditingFeatures when viewed over HTTP\n<<option chkForceMinorUpdate>> Treat edits as MinorChanges by preserving date and time\n^^(override with Shift key when clicking 'done' or by pressing Ctrl-Shift-Enter^^\n<<option chkConfirmDelete>> ConfirmBeforeDeleting\nMaximum number of lines in a tiddler edit box: <<option txtMaxEditRows>>\nFolder name for backup files: <<option txtBackupFolder>>\n<<option chkInsertTabs>> Use tab key to insert tab characters instead of jumping to next field\n<<option chkSinglePageMode>> Display one tiddler at a time\n<<option chkTopOfPageMode>> Always open tiddlers at the top of the page\n<<option chkBottomOfPageMode>> Always open tiddlers at the bottom of the page

Professor\nDepartment of Epidemiology\nUniversity of Washington\n\nHead of the Cancer Epidemiology Program\nDivision of Public Health Sciences\nFred Hutchinson Cancer Center\n\nM.D., 1978, University of Illinois\nM.P.H., 1983, University of Washington

Program in Epidemiology, ~MP-474\nFred Hutchinson Cancer Research Center\n1100 Fairview Ave North\nPO Box 19024\nSeattle, WA 98109\n206-667-5134\n206-667-4787 (fax)\ntvaughan@u.washington.edu

Welcome!

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<<importTiddlers>>

//{{{\nStory.prototype.tiddlerHistory= [];\nStory.prototype.maxTiddlers = 1;\nStory.prototype.closedHistory=[];\nStory.prototype.closedHistoryMax = 10;\n\nArray.prototype.moveToEnd = function(item)\n{\n this.remove(item);\n this.push(item);\n}\n\nStory.prototype.old_history_displayTiddler = Story.prototype.displayTiddler;\nStory.prototype.displayTiddler = function(srcElement,title,template,animate,slowly)\n{\n this.tiddlerHistory.moveToEnd(title);\n this.closedHistory.remove(title);\n var closeCount = this.tiddlerHistory.length - this.maxTiddlers;\n if (closeCount > 0)\n {\n var count = this.tiddlerHistory.splice (0,closeCount);\n for (var i=0; i<count.length;i++)\n {\n story.closeTiddler(count[i],false);\n }\n }\n story.old_history_displayTiddler(null,title,template,animate,slowly);\n}\n\nStory.prototype.old_history_closeTiddler = Story.prototype.closeTiddler;\nStory.prototype.closeTiddler = function(title,animate,slowly)\n{\n this.tiddlerHistory.remove(title);\n this.closedHistory.remove(title);\n this.closedHistory.unshift(title);\n story.old_history_closeTiddler.apply(this,arguments);\n}\n\nStory.prototype.displayTiddlers = function(srcElement,titles,template,animate,slowly)\n{\n for(var t = titles.length-1;t>=0;t--)\n {\n this.tiddlerHistory.moveToEnd(titles[t]);\n this.closedHistory.remove(titles[t]);\n this.old_history_displayTiddler(srcElement,titles[t],template,animate,slowly);\n }\n}\n\nconfig.commands.history={\n text: "history",\n tooltip: "re-open a closed tiddler"};\n\nconfig.commands.history.handler = function(event,src,title)\n{\n var popup = Popup.create(src);\n if(popup)\n {\n if (!story.closedHistory.length)\n createTiddlyText(popup,"No history");\n else\n {\n var c = Math.min(story.closedHistory.length,story.closedHistoryMax);\n for (i=0; i<c;i++ )\n {\n createTiddlyLink(createTiddlyElement(popup,"li"),story.closedHistory[i],true);\n }\n }\n }\n Popup.show(popup,false);\n event.cancelBubble = true;\n if (event.stopPropagation) event.stopPropagation();\n return false;\n}\n//}}}

This information taken from Julian Knight's TiddlyWiki, which can be [[found here|http://knighjm.googlepages.com/knightnet-default-tw.html]].\n\nMacros let you write tiddlers containing more exotic objects than just text. 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Note: Put quotes around the label if needing spaces<<br>>where: ''ID''=cookie name to be used to save the state of the slider, ''Tiddler''=name of the tiddler to include in the slider, ''Label''=label text of the slider button, ''tooltip''=text of the buttons tooltip|{{{<<slider ID Tiddler [Label] [toolTip]>>}}}|\n|sparkline|Produces a sparkline graphic<<br>>e.g. <<sparkline 163 218 231 236 232 266 176 249 289 1041 1835 2285 3098 2101 1755 3283 3353 3335 2898 2224 1404 1354 1825 1839 2142 1942 1784 1145 979 1328 1611>>|{{{<<sparkline num1 num2 ... numN>>}}}|\n|tabs|Display Tabbed content (contents of tab provided by another tiddler)|{{{<<tabs indentifier tabLabel tabName Tiddler>>}}}|\n|tag|Display a Tag ~PopUp<<br>><<tag _Config>>|{{{<<tag tagName>>}}}|\n|tagChooser|Used in EditTemplate to add tags to the tags field. 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This string can be a combination of ordinary text, with some special characters that get substituted by parts of the date:\n* DDD - day of week in full (eg, "Monday")\n* DD - day of month, 0DD - adds a leading zero\n* MMM - month in full (eg, "July")\n* MM - month number, 0MM - adds leading zero\n* YYYY - full year, YY - two digit year\n* hh - hours\n* mm - minutes\n* ss - seconds\n!Notes\nIf you need to supply a parameter that should be evaluated (e.g. a JavaScript variable), enclose the parameter in {{{{{}}} and {{{}}}}} rather than quotes. Note however, that the scope used in the evaluation is {{{global}}} rather than {{{local}}}. In other words, the evaluation is done ''before'' the parameter is passed to the macro/plugin so it cannot access any of the variables or functions defined within the macro/plugin.\n!Commands supported by the toolbar macro\n{{{\nconfig.commands = {\n closeTiddler: {text: "close", tooltip: "Close this tiddler"},\n closeOthers: {text: "close others", tooltip: "Close all other tiddlers"},\n editTiddler: {text: "edit", tooltip: "Edit this tiddler", readOnlyText: "view", readOnlyTooltip: "View the source of this tiddler"},\n saveTiddler: {text: "done", tooltip: "Save changes to this tiddler", readOnlyText: "done", readOnlyTooltip: "View this tiddler normally"},\n cancelTiddler: {text: "cancel", tooltip: "Undo changes to this tiddler", hideReadOnly: true},\n deleteTiddler: {text: "delete", tooltip: "Delete this tiddler", warning: "Are you sure you want to delete '%0'?", hideReadOnly: true},\n permalink: {text: "permalink", tooltip: "Permalink for this tiddler"},\n references: {text: "references", tooltip: "Show tiddlers that link to this one", popupNone: "No references"},\n jump: {text: "jump", tooltip: "Jump to another open tiddler"}\n };\n}}}\n(Julian Knight, 2006-04-06)\n<part tagging hidden>\nProduces a list (NB: <ul> ''not'' a popup) of links to tiddlers that carry the specified tag. If no tag is specified, it looks for tiddlers tagged with the name of the current tiddler.\nIn HTML, the list is formatted like so:\n{{{\n<ul>\n<li class="listTitle">List title label</li>\n<li><a class="tiddlyLink ..." href="javascript:;" onclick="..."\n refresh="link" tiddlyLink="ExampleOne">ExampleOne</a></li>\n</ul>\n}}}\n</part>\n<part tags hidden>\n<<allTags>>\n</part>

[[Home|Welcome!]]\n[[Contact Information]]\n[[Background]]\n[[Research Interests]]\n[[Publications]]\n----\n!!!!!In my spare time<<br>>[[Photography|http://gallery.tvaughan.org]]

\n<div class='toolbar' macro='toolbar closeTiddler closeOthers +editTiddler permalink references jump'></div>\n<div class='title' macro='view title'></div>\n<div class='subtitle'><span macro='view modifier link'></span>, <span macro='view modified date [[DD MMM YYYY]]'></span> (<span macro='message views.wikified.createdPrompt'></span> <span macro='view created date [[DD MMM YYYY]]'></span>)</div>\n<div class='tagging' macro='tagging'></div>\n<div class='tagged' macro='tags'></div>\n<div class='viewer' macro='view text wikified'></div>\n<div class='tagClear'></div>\n

/***\n|Name|OpenTopPlugin|\n|Created by|SaqImtiaz|\n|Location|http://tw.lewcid.org/#OpenTopPlugin|\n|Version|0.1|\n|Requires|~TW2.x|\n!!!Description:\nOpen new tiddlers at the top of the screen.\n\n!!!Code\n***/\n//{{{\nStory.prototype.coreLewcidDisplayTiddler=Story.prototype.displayTiddler ;\nStory.prototype.displayTiddler =\nfunction(srcElement,title,template,unused1,unused2,animate,slowly)\n{\n var srcElement=null;\n if (document.getElementById(this.idPrefix + title))\n {story.closeTiddler(title);}\n this.coreLewcidDisplayTiddler(srcElement,title,template,unused1,unused2,animate,slowly);\n window.scrollTo(0,0);\n}\n//}}}

<<plugins>>

!!Link to Pubmed\nClick [[here| http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=vaughan%20tl%5BAuthor%5D]] for an automated Pubmed search, with links to abstracts and full text of publications. \n\nFeel free to email me for a reprint.\n\n!!Expanded list of publications (updated Dec 2009):\n\n*Reid BJ, Li X, Galipeau PC, Vaughan TL. Barrett’s Esophagus and Esophageal Adenocarcinoma: Time for a New Synthesis. Nature Cancer Reviews. (in press)\n\n*Figueroa JD, Terry MB, Gammon MD, Zhang FF, Vaughan TL, Risch HA, Kleiner D, Bennett WP, Fraumeni JF Jr, Chow WH. Cigarette smoking, body mass, gastro-esophageal reflux disease, and non-steroidal anti-inflammatory drug use and risk of subtypes of esophageal and gastric cancers by P53 overexpression. Cancer Causes & Control, 2009;20:361-368. [NIHMS 100106;PMCID Pending]\n\n*Farjah, F, Wood DE, Yanez ND III, Vaughan TL, Symons RG, Krishnadasan B, Flum DR. Racial disparities among patients with lung cancer who were recommended operative therapy. Archives Surgery, 2009;144:14-18. [NIHMS 107169; PMCID Pending]\n\n*Thompson OM, Beresford SAA, Kirk EA, Vaughan TL. Vegetable and Fruit Intake and Risk of Barrett’s Esophagus in Men and Women. Amer J Clin Nutrition, 2009;89:890-896. [NIHMS 104247; PMCID Pending]\n\n*<nowiki>Hold GL, Rabkin CS, Gammon MD, Berry SH, Smith MG, Lissowska J, Risch HA, Chow WH, Mowat NAG, Vaughan TL, El-Omar EM. CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. European J Cancer Prevention, 2009;18:117-9. [PMCID Pending]</nowiki>\n\n*<nowiki>Edelstein ZR, Bronner MP, Rosen SN, Vaughan TL. Risk factors for Barrett’s esophagus among patients with gastroesophageal reflux disease: A community clinic-based case-control study. Amer J Gastro, 2009;104:834-42. [NIHMS104117; PMCID PMC2714477]</nowiki>\n\n*Paulson TG, Maley CC, Li X, Li H, Sanchez CA, Chao DL, Odze RD, Vaughan TL, Blount PL, Reid BJ. Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. Clinical Cancer Research, 2009 May 15;15(10):3305-14. May 5 [Epub] [PMCID Pending]\n\n*<nowiki>Hoyo C, Schildkraut JM, Murphy SK, Chow WH, Vaughan TL, Risch HA, Marks JR, Jirtle RL, Calingeart B, Mayne ST, Fraumeni JF Jr., Gammon MD. IGF2R polymorphisms and risk of esophageal and gastric adenocarcinoma. Int J Cancer, 2009 Dec 1;125(11):2673-8.. [PMCID Pending]</nowiki>\n\n*Dong LM, Peters U, Kristal AR, Schenk JM, Sanchez CA, Rabinovitch PS, Blount PL, Odze RD, Ayub K, Reid BJ, Vaughan TL. Dietary supplement use and risk of neoplastic progression in esophageal adenocarcinoma: a prospective study. Nutrition and Cancer, 2008;60:39-48.\n\n*Navarro SA, Mayne ST, Risch HA,, Gammon MD, Vaughan TL, Chow WH, Dubrow R, Schoenberg J, Stanford JL, West AB, Rotterdam H, Blot WJ, Fraumeni JF, Jr. Food group intake and risk of subtypes of esophageal and gastric cancer. Int J Ca, 2008;123:852-60. \n\n*<nowiki>Wideroff L, Vaughan TL, Farin FM, Gammon MD, Risch H, Stanford JL, Chow WH. GST, NAT1, CYP1A1 Polymorphisms and Risk of Esophageal or Gastric Adenocarcinomas. Cancer Detection and Prevention, 2007;31:233-6.</nowiki>\n\n*Edelstein ZR, Farrow DC, Bronner MP, Rosen SN, Vaughan TL. Central adiposity and risk of Barrett's esophagus. Gastroenterology, 2007;133:403-11.\n\n*<nowiki>Siahpush SH, Vaughan TL, Lampe JN, Freeman R, Lewis SK, Odze RD, Blount PL, Ayub K, Rabinovitch PS, Reid BJ, Chen C. Longitudinal Study of IGF-I, IGFBP-3, and their Polymorphisms: Risk of Neoplastic Progression in Barrett's Esophagus. Cancer Epidemiology Biomarkers & Prevention, 2007;16 2387-2395.</nowiki>\n\n*Terry MB, Gammon MD, Zhang FF, Vaughan TL, Chow WH, Risch HA, Schoenberg JB, Mayne ST, Stanford JL, West AB, Rotterdam H, Blot WJ, Fraumeni JF, Jr., Santella RM. Alcohol Intake, Metabolism and Risk of Esophageal and Gastric Adenocarcinomas. Cancer Causes Control, 2007;18:1039-1046.\n\n*Risques RA, Vaughan TL, Li X Odze RD, Blount PL, Ayub K, Gallaher JL, Reid BJ, Rabinovitch PS. Leukocyte telomere length predicts cancer risk in patients with Barrett’s esophagus. Cancer Epidemiology Biomarkers & Prevention, 2007;16:2649-55.\n\n*Nason KS, Farrow DC, Haigh G, Lee SP, Bronner MP, Rosen SN, Vaughan TL. Gastric Fluid Bile Concentrations and Risk of Barrett’s Esophagus. Interactive Cardiovascular and Thoracic Surgery, 2007;6:304-7\n\n*Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, Vaughan TL, ~McColl KEL, Lissowska J, Shoenberg JB, Blot WJ, Mowat NAG, Fraumeni JF Jr, ~El-Omar EM. A functional polymorphism of Toll-like receptor 4 gene is associated with increased risk of gastric cancer and its precursors. Gastroenterology, 2007;132:905-12.\n\n*<nowiki>Galipeau PC, Li X, Blount PL, Maley CC, Sanchez CA, Odze RD, Ayub K, Self SG, Rabinovitch PS, Vaughan TL, Reid BJ. NSAIDs Modulate Risk of CDKN2A, TP53, and DNA Content for Future Esophageal Adenocarcinoma: Barrett’s Esophagus Prospective Cohort Study. PLoS Medicine 4(2), e67 doi:10.1371/journal.pmed.0040067</nowiki>\n\n*Sun LM, Li CI, Huang EY, Vaughan TL. Survival differences by race in nasopharyngeal carcinoma. Amer J Epidemiology 2007;165:271-8.\n\n*Holmes, RS, Vaughan TL, Epidemiology and pathogenesis of esophageal cancer. Sem Rad Oncology 2007;17:2-9.\n\n*Chao DL, Maley CC, Wu X, Farrow DC, Galipeau PC, Sanchez CA, Paulson TG, Rabinovitch PS, Reid BJ, Spitz MR, Vaughan TL. Mutagen sensitivity and neoplastic progression in patients with Barrett’s esophagus. Cancer Epidemiology Biomarkers & Prevention 2006;15:1935-40.\n\n*Chang CK, Astrakianakis G, Thomas DB, Seixas NS, Camp JE, Ray RM, Gao DL, Wernli KJ, Li W, Fitzgibbons DE, Vaughan TL, Checkoway H. Risks of Gallbladder Cancer and Occupational Exposures among Shanghai Female Textile Workers – A ~Case-Cohort Study. Amer J Indus Med 2006;49:690-8.\n\n*Littman AJ, Vaughan TL. Cancer of the Sinonasal Cavities. Cancer Epidemiology and Prevention. Eds. Schottenfeld and Fraumeni, 2006.\n\n*Mayne ST, Risch HA, Dubrow R, Chow WH, Gammon MD, Vaughan TL, Fraumeni JF Jr. Re: Carbonated soft drink consumption and risk of esophageal and gastric adenocarcinoma (authors' reply) JNCI 2006;98:644-46.\n\n*Vaughan TL. Gastrointestinal Cancers. Fundamentals of Ecogenetics. Eds. Costa LG and Eaton DL. J. Wiley & Sons, 2006.\n\n*Vaughan TL, Reid BJ. Author reply to “Non-steroidal anti-inflammatory drugs and oesophageal adenocarcinoma: epidemiology needs randomised controlled trials to correct for bias." Lancet Oncology 2006;7:8-9.\n\n*Mayne ST, Risch HA, Dubrow R, Chow WH, Gammon MD, Vaughan TL, Borchardt L, Schoenberg JB, Stanford JL, West AB, Rotterdam H, Blot WJ, Fraumeni JF Jr. Carbonated soft drink consumption and risk of esophageal and gastric adenocarcinoma. JNCI 2006;98:72-75. \n\n*Chang CK, Astrakianakis G, Thomas DB, Seixas NS, Ray RM, Gao DL, Wernli KJ, Fitzgibbons DE, Vaughan TL, Checkoway H. Occupational exposures and risks of liver cancer among Shanghai female textile workers – a case-control study. Int J Epidem 2006;35:361-369.\n\n*Vaughan TL Dong LM, Blount PL, Ayub K, Odze RD, Sanchez CA, Rabinovitch PS, Reid BJ. Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett’s oesophagus: a prospective study. Lancet Oncology 2005;6:945-52.\n\n*Sun ~L-M, Epplein E, Li CI, Vaughan TL, Weiss NS. Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles and the San Francisco Metropolitan Area, 1992-2002. Amer J Epidem 2005;162:1174-1178.\n\n*Kristal AR, Blount PL, Schenk JM, Sanchez CA, Rabinovitch PS, Odze RD, Standley J, Vaughan TL, Reid BJ. Low-fat, high fruit and vegetable diets and weight loss do not affect biomarkers of cellular proliferation in Barrett Esophagus. Cancer Epidem Biomarkers Prev 2005;14:2377-2383.\n\n*Littman AJ, Jackson LA, Vaughan TL. Chlamydia pneumoniae and lung cancer: epidemiologic evidence. Cancer Epidem Biomarkers & Prev 2005;14:773-8. \n\n*Trivers KF, De Roos AJ, Gammon MD, Vaughan TL, Risch HA, Olshan AF, Schoenberg JB, Mayne ST, Stanford JL, Rotterdam H, West AB, Fraumeni JF, Jr. Chow WH. Demographic and Lifestyle Predictors of Survival in Patients with Esophageal or Gastric Cancers. Clinical Gastro and Hepatology 2005;3:225-230.\n\n*Littman AJ, Jackson LA, White E, Thornquist M, Gaydos C, Goodman GE, Vaughan TL. Chlamydia pneumoniae infection and risk of Lung cancer. Cancer Epidemiology Biomarkers & Prevention 2004;13:1624-30.\n\n*Soloman C, White E, Kristal A, Vaughan TL. Melanoma and lifetime UV exposure. Cancer Causes and Control, 2004;15:893-902.\n\n*Littman AJ, Thornquist MD, White E, Jackson LA, Goodman GE, Vaughan TL. Prior lung disease and risk of lung cancer in a large prospective study. Cancer Causes and Control 2004;15:819-827.\n\n*Littman AJ, Jackson LA, White E, Thornquist MD, Gaydos CA, Vaughan TL. Interlaboratory reliability of Chlamydia pneumoniae immunoglobulin A and G antibody titers using the microimmunfluorescence test, Clinical and Diagnostic Laboratory Immunology 2004;11:615-617.\n\n*Gammon MD, Terry MB, Arber N, Chow WH, Risch HA, Vaughan TL, Schoenberg JB, Mayne ST, Stanford JL, Rotterdam H, West AB, Fraumeni, JF Jr., Weinstein IB, Hibshoosh H. NSAID use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: A population-based Study. Cancer Epidemiology Biomarkers & Prevention 2004;13:34-39.\n\n*Plaskon LS, Penson D, Vaughan TL, Stanford JL. Cigarette smoking and increased prostate cancer risk in middle-aged men. Cancer Epidemiology Biomarkers & Prevention 2003;12:604-9.\n\n*Engel LS, Chow WH, Vaughan TL, Gammon MD, Risch HA, Mayne ST, Blaser MJ, Schoenberg JB, Stanford JL, Blot WJ, Gail M, Fraumeni JF Jr. Population attributable risks of esophageal and gastric cancers. JNCI 2003;95:1404-13.\n\n*~Nazar-Stewart V, Vaughan TL, Stapleton P, Van Loo J, ~Nicol-Blades B, Eaton DL. A ~Population-Based Study of Glutathione ~S-Transferase M1, T1 and P1 Genotypes and Risk for Lung Cancer. Lung Cancer 2003;40:247-58.\n\n*Sweeney C, ~Nazar-Stewart V, Stapleton PL, Eaton DL, Vaughan TL. Glutathione ~S-transferase (GST) M1, T1 and P1 polymorphisms and survival among lung cancer patients. Cancer Epidemiology Biomarkers & Prevention 2003;12:527-33.\n\n*~El-Omar EM, Rabkin CS, Gammon MD, Vaughan TL, Risch HA, Goedert JJ, Blot WJ, Fraumeni Jr. JF, Chow WH. Increased risk of non-cardia gastric cancer associated with pro-inflammatory cytokine gene polymorphisms. Gastroenterology 2003;124:1193-201.\n\n*Rudolph RE, Vaughan TL, Kristal AR, Blount PL, Levine DS, Galipeau PC, Prevo LJ, Sanchez CA, Rabinovitch PS, Reid BJ. Serum selenium in relation to markers of neoplastic progression among persons with Barrett’s esophagus. JNCI 2003;95:750–7.\n\n*Teschke K, Olshan AF, Daniels JL, De Roos AJ, Parks CG, Schulz M, Vaughan TL. Occupational exposure assessment in case-control studies: Opportunities for improvement. Occup Environ Med 2002:59:575-93.\n\n*Engel LS, Vaughan TL, Gammon MD, Chow WH, Risch HA, Dubrow RD, Mayne ST, Schoenberg JB, Stanford JL, West BA, Blot WJ, Fraumeni JF Jr. Occupation and risk of esophageal and gastric cancers. Amer J Indus Med 2002;42:11-22.\n\n*Vaughan TL, Kristal AR, Blount PL, Levine DS, Galipeau PC, Prevo LJ, Sanchez CA, Rabinovitch PS, Reid BJ. NSAID use, BMI, and anthropometry in relation to genetic and cell cycle abnormalities in Barrett's esophagus. Cancer Epidemiology Biomarkers & Prevention 2002;11:745-52.\n\n*Luce D, Leclerc A, Bégin D, Demers PA, Gérin M, Orlowski E, Kogevinas M, Belli S, Bugel I, ~Bolm-Audorff U, Brinton LA, Comba P, Hardell L, Hayes RB, Magnani C, Merler E, ~Preston-Martin S, Vaughan TL, Zheng W, Boffetta P. Sinonasal cancer and occupational exposures: a pooled analysis of 12 case-control studies. Cancer Causes Control 2002;13:147-157.\n\n*Vaughan TL. The Esophagus. Cancer Precursors: Epidemiology, Detection and Prevention. Franco EL, Rohan TE, eds. New York: ~Springer-Verlag, 2002, pp. 96‑116.\n\n*Mayne ST, Risch H, Dubrow R, Chow WH, Blot W, Gammon M, Vaughan TL, Farrow DC, Schoenberg J, Stanford JL, Ahsan H, Fraumeni, JF Jr. Nutrient intake and risk of adenocarcinomas of the esophagus and gastric cardia Cancer Epidemiology Biomarkers & Prevention 2001;10:1055-1062.\n\n*Dhillon PK, Farrow DC, Vaughan TL, Chow ~W-H, Risch HA, Gammon MD, Mayne ST, Stanford JL, Schoenberg JB, Ahsan H, Dubrow R, West AB, Rotterdam H, Blot WJ , Fraumeni JF Jr. Family history of cancer and risk of esophageal and gastric cancer in the United States. Internat J Cancer 2001;93:148-52.\n\n*Jackson LA, Wang SP, ~Nazar-Stewart V, Grayston JT, Vaughan TL, Association of Chlamydia pneumoniae ~IgA seropositivity and risk of lung cancer. Cancer Epidemiology Biomarkers & Prevention 2000; 9:1263 – 1266.\n\n*Sweeney C, Farrow DC, Schwartz SM, Eaton DL, Checkoway H, Vaughan TL. Glutathione S-transferase M1, T1 and P1 polymorphisms as risk factors for renal cell carcinoma: a case-control study. Cancer Epidemiology Biomarkers & Prevention 2000;9:449-454.\n\n*Vaughan TL, Stewart PA, Teschke K, Lynch CF, Swanson GM, Lyon JL, Berwick M. Occupational Exposure to Formaldehyde and Wood Dust and Risk of Nasopharyngeal Carcinoma. Occupational and Environmental Medicine 2000;57:376-384.\n\n*Rudolph RE, Vaughan TL, Storer B, Haggitt RC, Levine DS, Reid BJ. Barrett’s esophagus: the effect of segment length on the risk of neoplastic progression. Annals Internal Medicine 2000;132:612-620.\n\n*Farrow DC, Vaughan TL, Sweeney C, Gammon MD, Chow WH, Risch HA, Stanford JL, Hansten P, Mayne ST, Schoenberg JB, Rotterdam H, Ahsan H, West B, Dubrow R, Fraumeni JF Jr, Blot WJ. Gastroesophageal reflux disease, use of H2 Receptor antagonists, and risk of esophageal and gastric cancer. Cancer Causes & Control 2000;11:231-238.\n\n*Moe G, Kristal AR, Levine DS, Vaughan TL, Reid BJ. Waist to hip ratio, weight gain, dietary and serum selenium are associated with DNA content flow cytometry in Barrett’s esophagus. Nutrition and Cancer 2000;36:7-13.\n\n*~Nazar-Stewart V, Vaughan TL, Burt RD, Chen C, Berwick M, Swanson GM. Glutathione ~S-Transferase M1 and Susceptibility to Nasopharyngeal Carcinoma. Cancer Epidemiology Biomarkers & Prevention 1999;8:547-551.\n\n*Teschke K, Marion SA, Vaughan TL, Morgan MS, Camp J. Exposures to wood dust in US Industries and occupations, 1979-1997. Amer Indus Hyygiene Assoc J 1999;35:581-589.\n\n*Farrow DC, Vaughan TL, Berwick M, Lynch CF, Swanson GM, Lyon JL. Diet and nasopharyngeal cancer in a low-risk population. Internat J Cancer 1998;78:675-9. \n\n*Vaughan TL, Farrow DC, Hansten P, Chow WH, Gammon MD, Risch HA, Stanford JL, Schoenberg JB, Mayne ST, Rotterdam H, Dubrow R, Ahsan H, West B, Blot WJ, Fraumeni JF Jr. Risk of esophageal and gastric adenocarcinoma in relation to use of calcium channel blockers, asthma drugs and other medications that promote gastroesophageal reflux. Cancer Epidem Biomarkers and Prev 1998;7:749-756.\n\n*Demers PA, Boffetta P, Kogevinas M, Battista G, Belli S, Blair A, ~Bolm-Audorf U, Brinton LA, Colin D, Comba P, Gerin M, Hardell L, et al., Vaughan TL, et al. Cancer Risk from Occupational Exposure to Wood Dust. IARC Technical Report No. 30, Lyon, 1998.\n\n*Lenaway DD, Koepsell TD, Vaughan TL, van Belle G, Shy K, ~Cruz-Uribe F. Evaluation of a public-private certified nurse-midwife maternity program for indigent women. Amer J Pub Health 1998;88:675-79.\n\n*Chow WH, Blaser MJ, Blot WJ, Gammon MD, Vaughan TL, Risch HA, ~Perez-Perez GI, Schoenberg JB, Stanford JL, Rotterdam H, Fraumeni JF Jr. An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma. Cancer Research 1998;58:588-90. \n\n*Chow WH, Blot WJ, Vaughan TL, Risch HA, Gammon MD, Stanford JB, Dubrow R, Schoenberg JB, Mayne ST, Farrow DC, Ahsan H, West AB, Rotterdam H, Niwa S, Fraumeni, JF Jr. Body mass index and risk of adenocarcinoma of the esophagus and gastric cardia. JNCI 1998;90:150-155.\n\n*Farrow DC, Vaughan TL, Hansten P, Stanford JL, Gammon MD, Risch HA, Chow WH, Dubrow R, Ahsan H, Mayne ST, Schoenberg JB, Sweeney C, Rotterdam H, West B, Fraumeni JF Jr, Blot WJ. Use of aspirin and other non-steroidal anti-inflammatory drugs and risk of gastric and esophageal cancer. Cancer Epidemiology Biomarkers and Prevention 1998;7:97-102.\n\n*Engel LS, Keifer MC, Checkoway H, Robinson LR, Vaughan TL. Neurological function in farm workers exposed to organophosphate pesticides. Arch Environ Health 1998;53:7-14.\n\n*Bruemmer B, White E, Vaughan TL, Cheney CL. Fluid intake and the incidence of bladder cancer among middle aged men and women in a three county area of western Washington. Nutrition and Cancer 1997;29:163-168.\n\n*Vaughan TL, Stewart PA, Davis S, Thomas DB. Work in dry cleaning and the incidence of cancer of the oral cavity, larynx and esophagus. Occupational and Environmental Medicine 1997;54:692-695.\n\n*Gammon MD, Schoenberg JB, Ahsan H, Risch HA, Vaughan TL, et. al. Tobacco, alcohol and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia. JNCI 1997;89;1277-84.\n\n*~LeClerc A, Luce D, Demers PA, Boffetta P, et al., Vaughan TL, Zheng W. Sinonasal cancer and occupation. Results from the reanalysis of twelve case-control studies. American J Industrial Medicine 1997;31:153-165.\n\n*Burt RD, Vaughan TL, ~McKnight B, Davis S, Beckmann A, Smith AG, Nisperos B, Swanson GM, Berwick M. Associations between HLA type and nasopharyngeal carcinoma in U.S. caucasians. Cancer Epidemiology Biomarkers and Prevention 1996;5:879-887.\n\n*Alexander BH, Checkoway H, van Netten C, Kaufman JD, Vaughan TL, Mueller BA, Faustman EM. Paternal occupational lead exposure and pregnancy outcome. Internat J Occupational Environmental Health 1996;2:280-285.\n\n*Leet T, Acquavella J, Lynch C, Anne M, Weiss NS, Vaughan TL, Checkoway H. Cancer incidence among alachlor manufacturing workers. American J Indus Med 1996;30:300-306.\n\n*Vaughan TL, Shapiro JA, Burt RD, Swanson GM, Berwick M, Lynch CF, Lyon JL. Nasopharyngeal cancer in a low-risk population: defining risk factors by histologic type. Cancer Epidemiology Biomarkers and Prevention 1996;5:587-593.\n\n*Bruemmer B, White E, Vaughan TL, Cheney CL. Nutient intake in relationship to bladder cancer among middle-aged men and women. American J Epidem 1996;144:485-495.\n\n*Alexander BH, Checkoway H, van Netten C, Muller CH, Ewers TG, Kaufman JD, Mueller BA, Vaughan TL, Faustman EM. Semen quality of men employed at a lead smelter. Occupational and Environmental Medicine 1996;53:411-416.\n\n*Farrow D, Vaughan TL. Determinants of survival following the diagnosis of esophageal adenocarcinoma. Cancer Causes and Control 1996;7:322-327.\n\n*Deleyiannis FWB, Thomas DB, Vaughan TL. Alcoholism: Independent predictor of survival in patients with head and neck cancer. JNCI 1996;88:542-549.\n\n*Koessel S, Theis MK, Vaughan TL, Koepsell TK, Weiss NS, Greenberg RS, Swanson GM. Socioeconomic status and the incidence of multiple myeloma. Epidemiology 1996;7:4-8.\n\n*Vaughan TL: Agents causing other respiratory cancers. Occupational and Environmental Respiratory Diseases. Harber P, Schenker M, Balmes J, eds. St. Louis, Mosby, 1996, pp. 608-615.\n\n*Taylor VM, Kramer MD, Vaughan TL, Peacock S. Increased risk of placenta previa among women of Asian race. Obstetrics and Gynecology 1995;86:805-808.\n\n*Demers PA, Kogevinas M, Boffetta P, et al., Vaughan TL, et al. Wood dust and sino-nasal cancer: a pooled re-analysis of twelve case-control studies. American J Industrial Medicine 1995;28:151-166.\n\n*Habel LA, Stanford JL, Vaughan TL, Weiss NS, Daling JR. Occupation and breast cancer risk in middle age women. J Occupational Environmental Medicine 1995;37:349-356.\n\n*Vaughan TL, Kiemeney LALM, ~McKnight B. Colorectal cancer in patients with esophageal adenocarcinoma. Cancer Epidemiology Biomarkers and Prevention 1995;4:93-98.\n\n*Vaughan TL, Davis S, Kristal A, Thomas DB. Obesity, alcohol and tobacco as risk factors for cancer of the esophagus: adenocarcinoma versus squamous cell carcinoma. Cancer Epidemiology Biomarkers and Prevention 1995;4:85-92.\n\n*Rogers MAM, Vaughan TL, Davis S, Thomas DB. Consumption of nitrate, nitrite and nitrosodimethylamine and the risk of upper aerodigestive tract cancer. Cancer Epidemiology Biomarkers and Prevention 1995;4:29-36.\n\n*Boyko EJ, Theis MK, Vaughan TL, ~Nicol-Blades B. Increased risk of inflammatory bowel disease associated with oral contraceptive use. American J Epidemiology 1994;140:268-78.\n\n*Taylor VM, Kramer MD, Vaughan TL, Peacock S. Placenta previa and prior cesarean section - how strong is the association? Obstetrics and Gynecology 1994;84:55-57.\n\n*Demers PA, Checkoway H, Vaughan TL, Weiss NS, Heyer NJ, Rosenstock L. Cancer incidence among Seattle and Tacoma firefighters: 1974-1989. Cancer Causes and Control 1994;5:126-35.\n\n*Hedberg K, Vaughan TL, White E, Davis S, Thomas DB. Alcoholism and cancer of the larynx: A case-control study. Cancer Causes and Control 1994;5:3-8.\n\n*Burt RD, Vaughan TL, Nisperos B, Swanson M, Berwick M. A protective association between the ~HLA-A2 antigen and nasopharyngeal carcinoma in U.S. Caucasians. Internat J Cancer 1994;56:465-467.\n\n*Rogers MAM, Thomas DB, Davis S, Vaughan TL, Nevissi AE. A case-control study of element levels and cancer of the upper aerodigestive tract. Cancer Epidemiology Biomarkers and Prevention 1993;2:305-312.\n\n*Taylor VM, Kramer MD, Vaughan TL, Peacock S. Placenta previa in relation to induced and spontaneous abortion: a population-based study. Obstetrics and Gynecology 1993;82:1-4.\n\n*Vaughan TL, Lee JAHL, Strader CH. Breast cancer incidence at a nuclear facility: Demonstration of a morbidity surveillance system. Health Physics 1993;64:349-354. \n\n*Demers PA, Vaughan TL, Koepsell TD, Lyon JL, Swanson GM, Greenberg RS, Weiss NS. A case-control study of multiple myeloma and occupation. American J Industrial Medicine 1993;23:629-39.\n\n*Goldoft M, Weiss NS, Vaughan TL, Lee JAH. Nasal melanoma (letter). Brit J Indus Medicine 1993;50:767-768.\n\n*Demers PA, Vaughan TL, Checkoway H, Weiss NS, Heyer NJ, Rosenstock L. Cancer identification using a tumor registry in occupational cohort studies in the United States. American J Epidemiology 1992;136:1232-1240.\n\n*Demers PA, Vaughan TL. Excess cancer among white-collar workers in studies based on death certificates (letter). J Occupational Medicine 1992;34:592-593.\n\n*Wortley P, Vaughan TL, Davis S, Morgan MS, Thomas DB. A case-control study of occupational risk factors for laryngeal cancer. British J Industrial Medicine 1992;49:837-844.\n\n*Burt RD, Vaughan TL, ~McKnight B. Descriptive epidemiology and survival analysis of nasopharyngeal carcinoma in the United States. Internat J Cancer 1992;52:549-556.\n\n*Boyle CA, Brann EA and the Selected Cancers Cooperative Study Group. Proxy respondents and the validity of occupational and other exposure data. Amer J Epidem 1992;136:712-21.\n\n*Thom D, Nelson L, Vaughan TL. Spontaneous abortion and subsequent adverse birth outcomes. Amer J Obstet Gyn 1992;166:111-116.\n\n*Bobo JK, Thapa PB, Gale JL, Vaughan TL, Gilchrist LD, Rivara FP. Response bias associated with asking former study participants to assist in new research. Psychol Reports 1991;68:355-359.\n\n*Demers PA, Vaughan TL, Schommer RR. Case-control study of occupation and brain tumor mortality. J Occupational Medicine 1991;33:1001-1006.\n\n*Rogers MAM, Thomas DB, Davis S, Weiss NS, Vaughan TL, Nevissi AE. A case-control study of oral cancer and prediagnostic concentrations of selenium and zinc in nail tissue. Internat J Cancer 1991;48:182-188.\n\n*Kramer MD, Taylor V, Hickok DE, Daling JR, Vaughan TL, Hollenbach KA. The association of maternal smoking with placenta previa. Epidemiology 1991;2:221-223.\n\n*Vaughan TL, Davis S. Wood dust exposure and squamous cell cancers of the upper respiratory tract. American J Epidemiology 1991;133:560-564.\n\n*Selected Cancers Cooperative Study Group. The association of selected cancers with service in the US military in Vietnam. III. Hodgkin's Disease, Nasal cancer, nasopharyngeal cancer and primary liver cancer. Archives Internal Medicine 1990;150:2495-2505.\n\n*Selected Cancers Cooperative Study Group. The association of selected cancers with service in the US military in Vietnam. II. Soft tissue and other sarcomas. Archives Internal Medicine 1990;150:2485-249.\n\n*Selected Cancers Cooperative Study Group. The association of selected cancers with service in the US military in Vietnam. I. ~Non-Hodgkin's lymphoma. Archives Internal Medicine 1990;150:2473-2483.\n\n*Vaughan TL: Wood dust exposure and cancers of the upper respiratory tract. Occupational Epidemiology. Sakurai H, Okazaki I, Kazuyjke O, eds. Amsterdam: Excerpta Medica, 1990: 129-132.\n\n*Vaughan TL: Formaldehyde in the home: A cancer risk? Washington Public Health 1990;8:34-35.\n\n*Daniell WE, Vaughan TL, Millies BA. Pregnancy outcomes among female flight attendants. Aviation and Space Environmental Medicine 1990;61:840-844. \n\n*Van Den Eden SK, Karagas MR, Daling JR, Vaughan TL. A case-control study of the relationship between maternal smoking and congenital malformations. Paediatric and Perinatal Epidemiology 1990;4:147-155.\n\n*Rossing MA, Vaughan TL, ~McKnight B. Diet and pharyngeal cancer. International J Cancer 1989;44:593-597.\n\n*Vaughan TL. Wood exposure and nasal cancer (letter). J Occupational Medicine. 1989;31:939-941.\n\n*Vaughan TL. Occupation and squamous cell cancers of the pharynx and sinonasal cavity. American J Industrial Medicine 1989:16:493-510.\n\n*Diwan VK, Vaughan TL, Yang CY. Maternal smoking in relation to the incidence of early neonatal jaundice. Gynecologic and Obstetric Investigation 1989;27:22-25.\n\n*Schwartz DA, Vaughan TL, Heyer NJ, Koepsell TD, Lyon JL, Swanson GM, Weiss NS. ~B-Cell neoplasms and asbestos exposure. American J Industrial Medicine 1988;14:661-671.\n\n*Strader CH, Vaughan TL, Stergachis A. Use of nasal preparations and the incidence of sinonasal cancer. J Epidemiology Community Health 1988;42:243-248.\n\n*Burt R, Vaughan TL, Daling JR. Evaluating the risks of Cesarean section: low Apgar score in repeat cesarean section and vaginal deliveries. American J Public Health 1988;78:1312-1314.\n\n*Daniell WE, Vaughan TL. Paternal occupation in solvent-related occupations and adverse pregnancy outcomes. British J Industrial Medicine 1988;45:193-197.\n\n*Burbacher TM, Vaughan TL. Evaluating the public health of hazardous waste site communities: Current federal and state policies and recommendations for the Midway Landfill community. (Technical report). February 1987.\n\n*Vaughan TL. Formaldehyde exposure and cancers of the nose, sinus and pharynx. Final report to the U.S. Environmental Protection Agency. (Technical report). Contract No. 68-01-6280. April, 1986.\n\n*Vaughan TL, Strader C, Davis S, Daling JR. Formaldehyde and cancers of the pharynx, sinus and nasal cavity: II. Residential Exposures. International J Cancer 1986;38:685-688.\n\n*Vaughan TL, Strader C, Davis S, Daling JR. Formaldehyde and cancers of the pharynx, sinus and nasal cavity: I. Occupational Exposures. International J Cancer 1986;38:677-683.\n\n*Vaughan TL, ~McTiernan A: Diet in the etiology of cancer. Seminars in Oncology Nursing 1986;2:3-13.\n\n*Lee JAH, Vaughan TL, Diehr PH, Haertle RA: The recognition of novel occupational toxicity. Epidemiology and quantitation of environmental risk in humans from radiation and other agents. Castellani A, ed. New York: Plenum Press, 1985: 307-338.\n\n*Vaughan TL, Daling JR, Starzyk P: Fetal death and maternal occupation: an analysis of birth records in the State of Washington. J Occupational Medicine 1984:26;676-8.\n\n*Vaughan TL: The cardiovascular system. Medical Litigation Guide. Lane F, ed. Wilmette, IL: Callaghan, 1981: 30.01-30.39.\n\n*Vaughan TL: Data base design for a comprehensive cancer center. Proc Fourth Annual Symposium on Computer Applications in Medical Care, Washington D.C., 1980: 740-744.\n\n*Vaughan TL: Implications for interactive systems. Proc First International Symposium on Policy Analysis and Information Systems, Durham, NC, 1979: 672-673.\n

Over the past 30 years, the incidence of adenocarcinoma of the esophagus among white males in the US has increased almost 10-fold. Rapid increases among females and African American males also have been observed. This rapidly fatal cancer is becoming increasingly common in parts of western Europe as well. Esophageal adenocarcinoma is thought to develop in a series of potentially reversible steps, usually under conditions of chronic reflux. A substantial proportion, perhaps 10 - 15%, of those with chronic reflux develop a metaplastic epithelium (Barrett's esophagus). Those with metaplasia are at substantial risk, estimated at 0.5 - 1% per year, of developing dysplasia and eventually adenocarcinoma. Paralleling the histopathological changes are a number of cell cycle and genetic abnormalities, such as loss or mutation of tumor suppressor genes, telomere shortening and aneuploidy, resulting in increased genetic instability and eventually invasive cancer.\n\nOne major focus of our research is the identification of environmental and host factors that underlie this dramatic increase in incidence. We have approached this through population-based case-control studies of cancer, community-based case-control studies of newly diagnosed Barrett's, and a long-standing cohort study of persons with Barrett's. Determinants of genetic susceptibility to esophageal and gastric adenocarcinoma, e.g., genes involved in the biotransformation of xenobiotics, DNA repair, and immune response, are also being investigated. Polymorphisms in these genes may interact with environmental factors, such as in tobacco smoke or diet, in modifying risk in the general population. We are pursuing these issues in candidate gene studies as well as genome wide association studies that take advantage of the international BEACON consortium of esophageal cancer studies. Our eventual goal is to identify not only the major risk factors for esophageal adenocarcinoma, but the stage(s) of neoplastic progression at which they act. Such knowledge would be particularly helpful in designing primary and secondary prevention strategies.\n\nAnother major area of study in our research unit is occupational and environmental exposures (e.g., wood dust, formaldehyde), infectious diseases (e.g., Chlamydia pneumoniae, EBV) and genetic factors that may predispose to risk of lung and upper respiratory cancers, including sinonasal, nasopharyngeal, oral and laryngeal cancers. \n

<<search>><<saveChanges>>\n----\n!!!!Links of Interest for Cancer Patients<<br>>[[NCI News Center|http://www.cancer.gov/newscenter]] [[NCI Cancer Topics|http://www.cancer.gov/cancertopics]] [[ACS Cancer Reference|http://www.cancer.org/docroot/HOME/pff/pff_0.asp]]\n----\n!!!!Other Links of Interest<<br>>[[UW Dept. of Epidemiology|http://depts.washington.edu/epidem/]] [[Fred Hutchinson Cancer Center|http://fhcrc.org/]] [[Barrett's Esophagus Research Project|http://www.seattle.barrettsresearch.org/]][[SEER Cancer Registries|http://seer.cancer.gov/]] [[US Cancer Statistics - CDC|http://www.cdc.gov/cancer/npcr/uscs/]]\n\n

<<search>><<closeAll>><<permaview>><<newTiddler>><<newJournal 'DD MMM YYYY'>><<saveChanges>><<slider chkSliderOptionsPanel OptionsPanel 'options »' 'Change TiddlyWiki advanced options'>>

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Research & Publications

Thomas L Vaughan, MD, MPH

\nThese plugins are for extra TiddlyWiki mileage. They increase your filesize significantly, but they also add significantly to your file's capabilities.\n\n!Favorites from [[Abego Extensions|http://tiddlywiki.abego-software.de/]]\n*''~ForEachTiddlerPlugin'' lets you sort tiddlers and portions of tiddlers in many clever and helpful ways. I use it to index tags and tiddler titles. See [[Advanced ideas for tags]].\n*''~FormTiddlerPlugin'' and ''~DataTiddlerPlugin'' work together to [[Create forms with editable fields]].\n*The ''~IncludePlugin'' allows you to create a portal TW that accesses tiddlers from multiple other TiddlyWiki files as read-only tiddlers. Very nice for having a lot of data in one file without bloating the file.\n\n!Favorites from [[Lewcid Extensions|http://tw.lewcid.org/]]\n*''~FontsizePlugin'' lets you adjust the font size in a tiddler with + and - buttons.\n*''~IconMacro'' and ''~ToolbarIconsPluigin'' let you replace the usual TW features with icons.\n*''~SplashScreenPlugin'' calls up an introductory message while users wait for your file to open.\n\n!Favorites from [[TiddlyTools|http://www.tiddlytools.com/]]\n*''~NestedSlidersPlugin'' is a plugin for more advanced sliders than you can get from the [[Slider macros]].\n*''~SearchOptionsPlugin''. When this plugin is loaded and you do a search, you get a list of tiddlers containing the word you are searching for, rather than having all those tiddlers open. I don't have it installed here, because I want newbies to see what happens normally with searching. But I think this plugin is a must.\n*''~CoreTweaks'' adds some helpful tweaks to the TW core.\n\n!From [[MonkeyPirate|http://mptw-beta.tiddlyspot.com/]]\n*''~SelectPaletteMacro'' is technically a macro, but I'm including it here. It lets you select from a dropdown list of color palettes, and automatically reconfigures your color scheme based on your selection. \n\n

/***\nhttp://tiddlystyles.com/#theme:DevFire\nAuthor: Clint Checketts\n***/\n\n/*{{{*/\nbody {\nbackground: #000;\n}\n/*}}}*/\n/***\n!Link styles /% ============================================================= %/\n***/\n/*{{{*/\n/* next two lines mod by TV to remove underlining of links */\n:link, \n:visited,\na,\na.button,\n#mainMenu a.button,\n#sidebarOptions .sliderPanel a{\n color: #ffbf00;\n border: 0;\n background: transparent;\n text-decoration: none;\n}\n\na:hover,\na.button:hover,\n#mainMenu a.button:hover,\n#sidebarOptions .sliderPanel a:hover\n#sidebarOptions .sliderPanel a:active{\n color: #ff7f00;\n border: 0;\n border-bottom: #ff7f00 1px dashed;\n background: transparent;\n}\n\n#displayArea .button.highlight{\n color: #ffbf00;\n background: #4c4c4c;\n}\n/*}}}*/\n/***\n!Header styles /% ============================================================= %/\n***/\n/*{{{*/\n.header{\n border-bottom: 2px solid #ffbf00;\n color: #fff;\n}\n\n.headerForeground a {\n color: #fff;\n}\n\n.header a:hover {\n border-bottom: 1px dashed #fff;\n}\n/*}}}*/\n/***\n!Main menu styles /% ============================================================= %/\n***/\n/*{{{*/\n#mainMenu {color: #fff;}\n#mainMenu h1{\n font-size: 1.1em;\n}\n#mainMenu li,#mainMenu ul{\n list-style: none;\n margin: 0;\n padding: 0;\n}\n/*}}}*/\n/***\n!Sidebar styles /% ============================================================= %/\n***/\n/*{{{*/\n#sidebar {\n right: 0;\n color: #fff;\n border: 2px solid #ffbf00;\n border-width: 0 0 2px 2px;\n}\n#sidebarOptions {\n background-color: #4c4c4c;\n padding: 0;\n}\n\n#sidebarOptions a{\n margin: 0;\n color: #ffbf00;\n border: 0;\n}\n#sidebarOptions a:hover {\n color: #4c4c4c;\n background-color: #ffbf00;\n\n}\n\n#sidebarOptions a:active {\n color: #ffbf00;\n background-color: transparent;\n}\n\n#sidebarOptions .sliderPanel {\n background-color: #333;\n margin: 0;\n}\n\n#sidebarTabs {background-color: #4c4c4c;}\n#sidebarTabs .tabSelected {\n padding: 3px 3px;\n cursor: default;\n color: #ffbf00;\n background-color: #666;\n}\n#sidebarTabs .tabUnselected {\n color: #ffbf00;\n background-color: #5f5f5f;\n padding: 0 4px;\n}\n\n#sidebarTabs .tabUnselected:hover,\n#sidebarTabs .tabContents {\n background-color: #666;\n}\n\n.listTitle{color: #FFF;}\n#sidebarTabs .tabContents a{\n color: #ffbf00;\n}\n\n#sidebarTabs .tabContents a:hover{\n color: #ff7f00;\n background: transparent;\n}\n\n#sidebarTabs .txtMoreTab .tabSelected,\n#sidebarTabs .txtMoreTab .tab:hover,\n#sidebarTabs .txtMoreTab .tabContents{\n color: #ffbf00;\n background: #4c4c4c;\n}\n\n#sidebarTabs .txtMoreTab .tabUnselected {\n color: #ffbf00;\n background: #5f5f5f;\n}\n\n.tab.tabSelected, .tab.tabSelected:hover{color: #ffbf00; border: 0; background-color: #4c4c4c;cursor:default;}\n.tab.tabUnselected {background-color: #666;}\n.tab.tabUnselected:hover{color:#ffbf00; border: 0;background-color: #4c4c4c;}\n.tabContents {\n background-color: #4c4c4c;\n border: 0;\n}\n.tabContents .tabContents{background: #666;}\n.tabContents .tabSelected{background: #666;}\n.tabContents .tabUnselected{background: #5f5f5f;}\n.tabContents .tab:hover{background: #666;}\n/*}}}*/\n/***\n!Message area styles /% ============================================================= %/\n***/\n/*{{{*/\n#messageArea {background-color: #666; color: #fff; border: 2px solid #ffbf00;}\n#messageArea a:link, #messageArea a:visited {color: #ffbf00; text-decoration:none;}\n#messageArea a:hover {color: #ff7f00;}\n#messageArea a:active {color: #ff7f00;}\n#messageArea .messageToolbar a{\n border: 1px solid #ffbf00;\n background: #4c4c4c;\n}\n/*}}}*/\n/***\n!Popup styles /% ============================================================= %/\n***/\n/*{{{*/\n.popup {color: #fff; background-color: #4c4c4c; border: 1px solid #ffbf00;}\n.popup li.disabled{color: #fff;}\n.popup a {color: #ffbf00; }\n.popup a:hover { background: transparent; color: #ff7f00; border: 0;}\n.popup hr {color: #ffbf00; background: #ffbf00;}\n/*}}}*/\n/***\n!Tiddler Display styles /% ============================================================= %/\n***/\n/*{{{*/\n.title{color: #fff;}\nh1, h2, h3, h4, h5 {\n color: #fff;\n background-color: transparent;\n border-bottom: 0px solid #333;\n}\n\n.subtitle{\n color: #666;\n}\n\n.viewer {color: #fff; }\n\n.viewer table{background: #666; color: #fff;}\n\n.viewer th {background-color: #996; color: #fff;}\n\n.viewer pre, .viewer code {color: #ddd; background-color: #4c4c4c; border: 1px solid #ffbf00;}\n\n.viewer hr {color: #666;}\n\n.tiddler .button {color: #4c4c4c;}\n.tiddler .button:hover { color: #ffbf00; background-color: #4c4c4c;}\n.tiddler .button:active {color: #ffbf00; background-color: #4c4c4c;}\n\n.toolbar {\n color: #4c4c4c;\n}\n\n.toolbar a.button,\n.toolbar a.button:hover,\n.toolbar a.button:active,\n.editorFooter a{\n border: 0;\n}\n\n.footer {\n color: #ddd;\n}\n\n.selected .footer {\n color: #888;\n}\n\n.highlight, .marked {\n color: #000;\n background-color: #ffe72f;\n}\n.editorFooter {\n color: #aaa;\n}\n\n.tab{\n-moz-border-radius-topleft: 3px;\n-moz-border-radius-topright: 3px;\n}\n\n.tagging,\n.tagged{\n background: #4c4c4c;\n border: 1px solid #4c4c4c; \n}\n\n.selected .tagging,\n.selected .tagged{\n background-color: #333;\n border: 1px solid #ffbf00;\n}\n\n.tagging .listTitle,\n.tagged .listTitle{\n color: #fff;\n}\n\n.tagging .button,\n.tagged .button{\n color: #ffbf00;\n border: 0;\n padding: 0;\n}\n\n.tagging .button:hover,\n.tagged .button:hover{\nbackground: transparent;\n}\n\n.selected .isTag .tagging.simple,\n.selected .tagged.simple,\n.isTag .tagging.simple,\n.tagged.simple {\n float: none;\n display: inline;\n border: 0;\n background: transparent;\n color: #fff;\n margin: 0;\n}\n\n.cascade {\n background: #4c4c4c;\n color: #ddd;\n border: 1px solid #ffbf00;\n}\n/*}}}*/

\n''TiddlyWiki uses Wiki style markup, a way of lightly "tagging" plain text so it can be transformed into HTML. To see the codes that create the following format samples, go into edit mode (by double-clicking within the tiddler or pressing the "edit" button in the hidden menu above). You might want to print out those codes to keep handy as you develop your portfolio. As you can see, you have a lot of control over your text's look and feel.''\n\n! Header Samples\n!Header 1\n!!Header 2\n!!!Header 3\n!!!!Header 4\n!!!!!Header 5\n\n! Text Formatting\n''Bold'' (note that the code is two apostrophes and ''not'' the quote mark)\n==Strike==\n__Underline__\n//Italic//\n\n! Word lists with words and their definitions\n;This is the word\n:This is its indented definition\n\n;This is the next entry in the word list \n:This is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definitionThis is its indented definition\n\n! Unordered Lists:\n* Lists are where its at\n* Just use an asterisk and you're set\n** To nest lists just add more asterisks...\n***...like this\n* You can also nest mixed list types\n## Like this\n\n! Ordered Lists\n# Ordered lists are pretty neat too\n## To nest, just add more octothorpes (pound signs)...\n### Like this\n* You can also\n** Mix list types\n*** like this\n# Pretty neat don't you think?\n\n! Tiddler links\nTo create a Tiddler link, just use a WikiWord or simply suround the link with double square [[brackets]]. It is quicker to make a WikiWord, but some find them ugly. The double square bracket method makes for a more normal look.\n\nNote that existing Tiddlers are in bold and empty Tiddlers are in italics. See Creating Tiddlers for details.\n\n! External Links\nYou can link to [[external sites|http://google.com]] with brackets. You can also Link To Folders on your machine or network shares.\n\n! Images\n[img[http://farm1.static.flickr.com/161/347371396_15f9f558ff.jpg]]\n\n\nTo do this, visit [[ImageShack|http://www.imageshack.us/]]. Select "Browse" to find an image on your computer that you want to upload. Select an image, press "OK/Open," and then press the "Host it!" button. After a short while (depending on your internet connection and image size), your image will upload and you will see a number of boxes with linking code for your uploaded image. Chose the Direct Link linking code. \n\nNote: You could use other photo hosting services, like Flickr, if you prefer. ImageShack is easy, but Flickr has a lot of power.\n\nEdit this tiddler to see how to formate the linking code.\n!Tables\n|!th1111111111|!th2222222222|\n|>| colspan |\n| rowspan |left|\n|~| right|\n|bgcolor(#DC1A1A):colored| center |\n|caption|c\n\n\n! Horizontal Rules\nYou can divide a tiddler into\n----\nsections by typing four dashes on a line by themselves.\n\n! Blockquotes\n<<<\nThis is how you do an extended, wrapped blockquote so you don't have to put angle quotes on every line.\n<<<\n>level 1\n>level 1\n>>level 2\n>>level 2\n>>>level 3\n>>>level 3\n>>level 2\n>level 1\n\n\nSuperscript: 2^^3^^=8\nSubscript: a~~ij~~ = -a~~ji~~\n@@highlight@@ Highlighting is working now it seems.\n@@color(green):green colored@@\n@@bgcolor(#ff0000):color(#ffffff):red colored@@ Hexadecimal numbers are often used for colors in computer codes.\n\nSource: [[Tid-Help - a primer for tiddlywiki|http://tidhelp.tiddlyspot.com/]]

<<toggleSideBar Sidebar "Hide sidebar" show>>\n[[MainMenu]]\n[[TabAll]]\n[[TabTimeline]]\n[[TabMoreShadowed]]\n[[SideBarOptionsOld]]\n[[SideBarOptions]]\n[[SideBarTabsOld]]\nAdvancedOptions\nPluginManager\nImportTiddlers\n\nThese InterfaceOptions for customising TiddlyWiki are saved in your browser\n\nYour username for signing your edits. Write it as a WikiWord (eg JoeBloggs)\n\n<<option txtUserName>>\n<<option chkSaveBackups>> SaveBackups\n<<option chkAutoSave>> AutoSave\n<<option chkRegExpSearch>> RegExpSearch\n<<option chkCaseSensitiveSearch>> CaseSensitiveSearch\n<<option chkAnimate>> EnableAnimations\n\n

/***\n|Name|UnformattedTextPlugin|\n|Source|http://www.TiddlyTools.com/#UnformattedTextPlugin|\n|Version|1.1.0|\n|Author|Eric Shulman - ELS Design Studios|\n|License|http://www.TiddlyTools.com/#LegalStatements <<br>>and [[Creative Commons Attribution-ShareAlike 2.5 License|http://creativecommons.org/licenses/by-sa/2.5/]]|\n|~CoreVersion|2.1|\n|Type|plugin|\n|Requires||\n|Overrides||\n|Description||\n\nAdd //extended quotes// around specific tiddler content to prevent any embedded formatting syntax from being processed by TiddlyWiki's rendering engine, so the content will appear exactly as entered into the tiddler (i.e., "raw text"), even when it contains character sequences that would normally be treated as TiddlyWiki formatting instructions.\n!!!!!Usage\n<<<\nThis plugin adds new wiki syntax for surrounding tiddler content so that it can be excluded from the TiddlyWiki formatting rules when it is rendered.\n//{{{\n"""content goes here"""\n//}}}\nor\n//{{{\n<nowiki>content goes here</nowiki>\n//}}}\nwhere:\n* {{{"""}}} //(three double-quote characters)// (or {{{<nowiki>}}} and {{{</nowiki>}}})^^\nmarks the start and end of the unformatted content^^\n<<<\n!!!!!Examples\n<<<\nContent containing TiddlyWiki formatting syntax can be shown with the syntax unchanged:\n{{{\n"""this text is //not italic// and <<not a macro>> and [[not a link]]"""\n<nowiki>this text is //not italic// and <<not a macro>> and [[not a link]]</nowiki>\n}}}\n"""this text is //not italic// and <<not a macro>> and [[not a link]]"""\n<nowiki>this text is //not italic// and <<not a macro>> and [[not a link]]</nowiki>\n\nNote that, although formatting syntax contained ''within'' the quoted content does not affect the style of the output, any formatting syntax ''surrounding'' the quoted content will still be applied. For example, the following unformatted output will be underlined:\n{{{\n__"""this text is //not italic// and <<not a macro>> and [[not a link]], but it IS underlined"""__\n}}}\n__"""this text is //not italic// and <<not a macro>> and [[not a link]], but it IS underlined"""__\n<<<\n!!!!!Installation\n<<<\nimport (or copy/paste) the following tiddlers into your document:\n''UnformattedTextPlugin'' (tagged with <<tag systemConfig>>)\n<<<\n!!!!!Revision History\n<<<\n''2006.09.21 [1.1.0]'' added alternative syntax: {{{<nowiki>...</nowiki>}}}\n''2005.11.07 [1.0.0]'' initial release\n<<<\n!!!!!Credits\n<<<\nThis feature was developed by EricShulman from [[ELS Design Studios|http:/www.elsdesign.com]]\n<<<\n!!!!!Code\n***/\n//{{{\nversion.extensions.unformattedText = {major: 1, minor: 1, revision: 0, date: new Date(2006,9,21)};\n\nconfig.formatters.push( {\n name: "rawText",\n match: "(?:\s\s\s"{3}|<nowiki>)",\n lookahead: "(?:\s\s\s"{3}|<nowiki>)((?:.|\s\sn)*?)(?:\s\s\s"{3}|</nowiki>)",\n handler: function(w)\n {\n var lookaheadRegExp = new RegExp(this.lookahead,"mg");\n lookaheadRegExp.lastIndex = w.matchStart;\n var lookaheadMatch = lookaheadRegExp.exec(w.source)\n if(lookaheadMatch && lookaheadMatch.index == w.matchStart)\n {\n var e = createTiddlyElement(w.output,"span",null,null,lookaheadMatch[1]);\n w.nextMatch = lookaheadMatch.index + lookaheadMatch[0].length;\n }\n }\n }\n)\n//}}}

\n<div class='toolbar' macro='toolbar closeTiddler closeOthers +editTiddler permalink references jump'></div>\n<div class='title' macro='view title'></div>\n<div class='viewer' macro='view text wikified'></div>\n<div class='tagging' macro='tagging'></div>\n\n<div class='tagClear'></div>\n

[>img[http://tvshare.eml.cc/research/tom_vaughan.jpg]]@@padding:0em 1em 0em 0em ;Choose links on the left to learn about me and my research. Other links (on the right) lead to resources for persons with cancer and selected other sites related to cancer epidemiology.@@

\nA TiddlyWiki FAQ - http://twfaq.tiddlyspot.com/\n\nA TiddlyDoc documentation site: http://doc.tiddlywiki.org/\n\nA Tiddly Guides wikipedia type document: http://tiddlywikiguides.org/index.php?title=TiddlyWiki_Guides\n\nThe Google Group devoted to TiddlyWiki: http://groups-beta.google.com/group/TiddlyWiki\n\nThis is the best tutorial for those who know a bit more: http://tiddlyspot.com/twhelp/\n\nTo learn some CSS code, here's a link: http://www.htmldog.com/reference/cssproperties/\n\n

!!!<<gradient horiz #fc3 #ffffff>>[[HowToUseLinks]]>>\n''There are a mulitude of ways to link in ~TiddlyWiki and most are listed here.''\n!!!<<gradient horiz #aaaaaa #bbbbbb #cccccc #eeeeee #ffffff>> Example>>\n|<<tiddler ./demoLink>> |\n<part demoLink hidden>\n[[Link to file|file:///D:/Digital Photos/100_0008.JPG]] @@color:#C06;''» »'' @@ ''Link to a file on local disk''\n\n{{{like this: [[Link to file|file:///D:/Digital Photos/100_0008.JPG]]}}}\n</part>\n\n<part uselinks>\n!!!<<gradient horiz #aaaaaa #bbbbbb #cccccc #eeeeee #ffffff>> Preview>>\n*How to use links\n1: TiddlyWiki @@color:#C06;''» »'' @@ ''Link to tiddlers with ~WikiWord titles''\n<<<\n{{{like this: TiddlyWiki - just use tiddler title}}}\n<<<\n----\n2: [[Tiddly Wiki]] @@color:#C06;''» »'' @@ ''Link to tiddlers with nonWikiWord titles (with spaces)''\n<<<\n{{{like this: [[Tiddly Wiki]] using double square brackets.}}}\n<<<\n----\n3: [[ordinary words|TiddlyWiki]] @@color:#C06;''» »'' @@ ''Link to tiddlers with ordinary words''\n<<<\n{{{like this: [[ordinary words|TiddlyWiki]]}}}\n{{{like this: [[ordinary words|Tiddly Wiki]]}}}\n<<<\n</part>\n----\n4: [[external site|http://www.osmosoft.com]] @@color:#C06;''» »'' @@ ''Link to external sites with ordinary words''\n<<<\n{{{like this: [[external site|http://www.osmosoft.com]]}}}\n<<<\n----\n5: <html><a href="http://www.osmosoft.com" target="_blank">External link using HTML</a></html> @@color:#C06;''» »'' @@ ''Link to external sites using ordinary words in HTML''\n<<<\n{{{like this: <html><a href="http://www.osmosoft.com" target="_blank">External link using HTML</a></html>}}}\n<<<\n----\n6: http://www.osmosoft.com @@color:#C06;''» »'' @@ ''Link to external sites using URL''\n<<<\n{{{like this: http://www.osmosoft.com}}}\n<<<\n----\n7: [[Link to file|file:///D:/Digital Photos/100_0008.JPG]] @@color:#C06;''» »'' @@ ''Link to a file on local disk''\n<<<\n{{{like this: [[Link to file|file:///D:/Digital Photos/100_0008.JPG]]}}}\n<<<\n7a:[[Link to relative file|file:../TiddlySpot/TiddlyWiki2.1/tiddlywikihelp.html]] @@color:#C06;''» »'' @@ ''Link to a relative file on local disk''\n{{{\nlike this:\n[[Link to relative file|file:../TiddlySpot/TiddlyWiki2.1/tiddlywikihelp.html]]\n}}}\n''Note:'' This link backs out of a folder on local disk called ''~TiddlySpot'' to the main directory then back into ''~TiddlySpot'' folder then to a subfolder called ''~TiddlyWiki2.1'' and then to a file called ''tiddlywikihelp.html''\n<<<\n<<<\n----\n8: [[Link to folder|file:///D:/Digital Photos/]] @@color:#C06;''» »'' @@ ''Link to a folder on local disk''\n<<<\n{{{like this: [[Link to folder|file:///D:/Digital Photos/]]}}}\n<<<\n----\n<part images>\n9: ''Link to external images'' @@color:#C06;''» »'' @@\n[img[Castle on the Danube|http://img480.imageshack.us/img480/6435/CastleOnDanube.jpg][http://img480.imageshack.us/img480/6435/CastleOnDanube.jpg]]\n<<<\n{{{\n[img[http://ecetera.com/image.jpg]]\n\nor with tool tip and link\n\n[img[tooltip|http://ecetera.com/image.jpg][http://another-link.com]]\n}}}\nlike this:\n{{{[img[Castle|img[http://img480.imageshack.us/img480/6435/CastleOnDanube.jpg]]}}}\n\nfloat right like this:\n{{{ [>img[Castle|http://img480.imageshack.us/img480/6435/CastleOnDanube.jpg]]}}}\n\nfloat left like this:\n{{{ [<img[Castle|http://img480.imageshack.us/img480/6435/CastleOnDanube.jpg]]}}}\n<<<\n----\n10: ''Using external image as a link in HTML'' @@color:#C06;''» »'' @@\n<html><a href="http://img480.imageshack.us/img480/7466/RainbowOverDanube.jpg" target="_blank"><img src="http://img480.imageshack.us/img480/7203/ParliamentHouseBudapest.jpg" width="240" height="160" alt="Castle on the Danube" /></a></html>\nParliament House Budapest\n(click to to see rainbow over the Danube)\n<<<\n{{{like this: <html><a href="http://img480.imageshack.us/img480/7466/RainbowOverDanube.jpg" target="_blank"><img src="http://img480.imageshack.us/img480/7203/ParliamentHouseBudapest.jpg" width="240" height="160" alt="Castle on the Danube" /></a></html>}}}\n<<<\n----\n</part>\n\n\n\n\n\n\nSource: [[TwHelp - TiddlyWiki help file for beginners |http://tiddlyspot.com/twhelp/#TWHelp-SearchResults]]

config.macros.toggleSideBar={};\n\nconfig.macros.toggleSideBar.settings={\n styleHide : "#sidebar { display: none;}\sn"+"#contentWrapper #displayArea { margin-right: 1em;}\sn"+"",\n styleShow : " ",\n arrow1: "«",\n arrow2: "»"\n};\n\nconfig.macros.toggleSideBar.handler=function (place,macroName,params,wikifier,paramString,tiddler)\n{\n var tooltip= params[1]||'toggle sidebar';\n var mode = (params[2] && params[2]=="hide")? "hide":"show";\n var arrow = (mode == "hide")? this.settings.arrow1:this.settings.arrow2;\n var label= (params[0]&&params[0]!='.')?params[0]+" "+arrow:arrow;\n var theBtn = createTiddlyButton(place,label,tooltip,this.onToggleSideBar,"button HideSideBarButton");\n if (mode == "hide")\n { \n (document.getElementById("sidebar")).setAttribute("toggle","hide");\n setStylesheet(this.settings.styleHide,"ToggleSideBarStyles");\n }\n};\n\nconfig.macros.toggleSideBar.onToggleSideBar = function(){\n var sidebar = document.getElementById("sidebar");\n var settings = config.macros.toggleSideBar.settings;\n if (sidebar.getAttribute("toggle")=='hide')\n {\n setStylesheet(settings.styleShow,"ToggleSideBarStyles");\n sidebar.setAttribute("toggle","show");\n this.firstChild.data= (this.firstChild.data).replace(settings.arrow1,settings.arrow2);\n }\n else\n { \n setStylesheet(settings.styleHide,"ToggleSideBarStyles");\n sidebar.setAttribute("toggle","hide");\n this.firstChild.data= (this.firstChild.data).replace(settings.arrow2,settings.arrow1);\n }\n\n return false;\n}\n\nsetStylesheet(".HideSideBarButton .button {font-weight:bold; padding: 0 5px;}\sn","ToggleSideBarButtonStyles");

/***\nhttp://tiddlystyles.com/#theme:DevFire\nAuthor: Clint Checketts modified by Tom Vaughan\n***/\n\n/*{{{*/\nbody {\nbackground: #000;\n}\n/*}}}*/\n/***\n!Link styles /% ============================================================= %/\n***/\n/*{{{*/\n/* next two lines mod by TV to remove underlining of links */\n:link, \n:visited,\na,\na.button,\n#mainMenu a.button,\n#sidebarOptions .sliderPanel a{\n color: #ffbf00;\n border: 0;\n background: transparent;\n text-decoration: none;\n}\n\na:hover,\na.button:hover,\n#mainMenu a.button:hover,\n#sidebarOptions .sliderPanel a:hover\n#sidebarOptions .sliderPanel a:active{\n color: #ff7f00;\n border: 0;\n border-bottom: #ff7f00 1px dashed;\n background: transparent;\n}\n\n#displayArea .button.highlight{\n color: #ffbf00;\n background: #4c4c4c;\n}\n/*}}}*/\n/***\n!Header styles /% ============================================================= %/\n***/\n/*{{{*/\n.header{\n border-bottom: 2px solid #ffbf00;\n color: #fff;\n}\n\n.headerForeground a {\n color: #fff;\n}\n\n.header a:hover {\n border-bottom: 1px dashed #fff;\n}\n/*}}}*/\n/***\n!Main menu styles /% ============================================================= %/\n***/\n/*{{{*/\n#mainMenu {color: #fff;}\n#mainMenu h1{\n font-size: 1.1em;\n}\n#mainMenu li,#mainMenu ul{\n list-style: none;\n margin: 0;\n padding: 0;\n}\n/*}}}*/\n/***\n!Sidebar styles /% ============================================================= %/\n***/\n/*{{{*/\n#sidebar {\n right: 0;\n color: #fff;\n border: 2px solid #ffbf00;\n border-width: 0 0 2px 2px;\n}\n#sidebarOptions {\n background-color: #4c4c4c;\n padding: 0;\n}\n\n#sidebarOptions a{\n margin: 0;\n color: #ffbf00;\n border: 0;\n}\n#sidebarOptions a:hover {\n color: #4c4c4c;\n background-color: #ffbf00;\n\n}\n\n#sidebarOptions a:active {\n color: #ffbf00;\n background-color: transparent;\n}\n\n#sidebarOptions .sliderPanel {\n background-color: #333;\n margin: 0;\n}\n\n#sidebarTabs {background-color: #4c4c4c;}\n#sidebarTabs .tabSelected {\n padding: 3px 3px;\n cursor: default;\n color: #ffbf00;\n background-color: #666;\n}\n#sidebarTabs .tabUnselected {\n color: #ffbf00;\n background-color: #5f5f5f;\n padding: 0 4px;\n}\n\n#sidebarTabs .tabUnselected:hover,\n#sidebarTabs .tabContents {\n background-color: #666;\n}\n\n.listTitle{color: #FFF;}\n#sidebarTabs .tabContents a{\n color: #ffbf00;\n}\n\n#sidebarTabs .tabContents a:hover{\n color: #ff7f00;\n background: transparent;\n}\n\n#sidebarTabs .txtMoreTab .tabSelected,\n#sidebarTabs .txtMoreTab .tab:hover,\n#sidebarTabs .txtMoreTab .tabContents{\n color: #ffbf00;\n background: #4c4c4c;\n}\n\n#sidebarTabs .txtMoreTab .tabUnselected {\n color: #ffbf00;\n background: #5f5f5f;\n}\n\n.tab.tabSelected, .tab.tabSelected:hover{color: #ffbf00; border: 0; background-color: #4c4c4c;cursor:default;}\n.tab.tabUnselected {background-color: #666;}\n.tab.tabUnselected:hover{color:#ffbf00; border: 0;background-color: #4c4c4c;}\n.tabContents {\n background-color: #4c4c4c;\n border: 0;\n}\n.tabContents .tabContents{background: #666;}\n.tabContents .tabSelected{background: #666;}\n.tabContents .tabUnselected{background: #5f5f5f;}\n.tabContents .tab:hover{background: #666;}\n/*}}}*/\n/***\n!Message area styles /% ============================================================= %/\n***/\n/*{{{*/\n#messageArea {background-color: #666; color: #fff; border: 2px solid #ffbf00;}\n#messageArea a:link, #messageArea a:visited {color: #ffbf00; text-decoration:none;}\n#messageArea a:hover {color: #ff7f00;}\n#messageArea a:active {color: #ff7f00;}\n#messageArea .messageToolbar a{\n border: 1px solid #ffbf00;\n background: #4c4c4c;\n}\n/*}}}*/\n/***\n!Popup styles /% ============================================================= %/\n***/\n/*{{{*/\n.popup {color: #fff; background-color: #4c4c4c; border: 1px solid #ffbf00;}\n.popup li.disabled{color: #fff;}\n.popup a {color: #ffbf00; }\n.popup a:hover { background: transparent; color: #ff7f00; border: 0;}\n.popup hr {color: #ffbf00; background: #ffbf00;}\n/*}}}*/\n/***\n!Tiddler Display styles /% ============================================================= %/\n***/\n/*{{{*/\n.title{color: #fff;}\nh1, h2, h3, h4, h5 {\n color: #fff;\n background-color: transparent;\n border-bottom: 0px solid #333;\n}\n\n.subtitle{\n color: #666;\n}\n\n.viewer {color: #fff; }\n\n.viewer table{background: #666; color: #fff;}\n\n.viewer th {background-color: #996; color: #fff;}\n\n.viewer pre, .viewer code {color: #ddd; background-color: #4c4c4c; border: 1px solid #ffbf00;}\n\n.viewer hr {color: #666;}\n\n.tiddler .button {color: #4c4c4c;}\n.tiddler .button:hover { color: #ffbf00; background-color: #4c4c4c;}\n.tiddler .button:active {color: #ffbf00; background-color: #4c4c4c;}\n\n.toolbar {\n color: #4c4c4c;\n}\n\n.toolbar a.button,\n.toolbar a.button:hover,\n.toolbar a.button:active,\n.editorFooter a{\n border: 0;\n}\n\n.footer {\n color: #ddd;\n}\n\n.selected .footer {\n color: #888;\n}\n\n.highlight, .marked {\n color: #000;\n background-color: #ffe72f;\n}\n.editorFooter {\n color: #aaa;\n}\n\n.tab{\n-moz-border-radius-topleft: 3px;\n-moz-border-radius-topright: 3px;\n}\n\n.tagging,\n.tagged{\n background: #4c4c4c;\n border: 1px solid #4c4c4c; \n}\n\n.selected .tagging,\n.selected .tagged{\n background-color: #333;\n border: 1px solid #ffbf00;\n}\n\n.tagging .listTitle,\n.tagged .listTitle{\n color: #fff;\n}\n\n.tagging .button,\n.tagged .button{\n color: #ffbf00;\n border: 0;\n padding: 0;\n}\n\n.tagging .button:hover,\n.tagged .button:hover{\nbackground: transparent;\n}\n\n.selected .isTag .tagging.simple,\n.selected .tagged.simple,\n.isTag .tagging.simple,\n.tagged.simple {\n float: none;\n display: inline;\n border: 0;\n background: transparent;\n color: #fff;\n margin: 0;\n}\n\n.cascade {\n background: #4c4c4c;\n color: #ddd;\n border: 1px solid #ffbf00;\n}\n/*}}}*/